RESEARCH / FUNCTIONAL BIOMATERIALS · 2023-07-06

From Printable Bioinks to Functional Therapeutic Biomaterials

Research published in 2023 connected Brinter-associated extrusion workflows with tissue-adhesive, antioxidant and controlled protein-delivery biomaterial systems, extending additive manufacturing beyond structure alone.

Adding biological function to printable materials

A 2023 study involving Tampere University and Brinter developed a pH-responsive hyaluronic-acid-based hydrogel system for injection and extrusion bioprinting. The material combined improved printability with tissue adhesion and antioxidant activity, illustrating how material chemistry and the manufacturing process can be designed together around an intended biomedical function.

Printing as part of a therapeutic delivery system

A separate 2023 study at Åbo Akademi University used the Brinter One platform to print nanocomposite hydrogels containing surface-modified mesoporous silica nanoparticles loaded with a model protein. The work connected material rheology, nanoparticle interactions, extrusion parameters and release behaviour in one manufacturing workflow.

  • pH-responsive and photocrosslinkable biomaterial systems.
  • Tissue adhesion and antioxidant functionality.
  • Nanoparticle-loaded hydrogels for biological cargo delivery.
  • Brinter One extrusion of nanocomposite biomaterial inks.
  • Process development linking printability with downstream therapeutic function.

Manufacturing function, not only geometry

Together, these studies are a useful historical proof point for Brinter's application-driven manufacturing philosophy. The target was not simply to reproduce a shape: material formulation, processability and the biological function of the printed construct were treated as connected engineering variables.

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