#Elsevier and #ScienceJournal – Polymer microsphere inks for semi-solid extrusion 3D printing at ambient conditions

Abstract https://www.sciencedirect.com/science/article/pii/S1751616124004156?dgcid=author Extrusion-based 3D printing methods have great potential for manufacturing of personalized polymer-based drug-releasing systems. However, traditional melt-based extrusion techniques are often unsuitable for processing thermally labile molecules. Consequently, methods that utilize the extrusion of semi-solid inks under mild conditions are frequently employed. The rheological properties of the semi-solid inks have a substantial impact […]

Wiley – Experimental investigation of PCL-based composite material fabricated using solvent-cast 3D printing process

Abstract https://onlinelibrary.wiley.com/doi/abs/10.1002/pat.6416?casa_token=WQcKEetHLSgAAAAA%3Alg7G6z9JBMJM0wxuWkL16agBgvuFZag7mTRWy7pvGBYfCzHwxTvcgOtXUfH7yVbRAa9NuSTpdua5V7E Bone tissue engineering relies on scaffolds with enhanced mechanical properties, achievable through 3D printing techniques. Our study focuses on enhancing mechanical properties using a solvent-cast 3D printing method. For this, poly-ε-caprolactone (PCL) reinforced with polyhydroxybutyrate (PHB), and synthetic fluorapatite (FHAp) nanopowders were utilized, immersed in a solution of dichloromethane (DCM) and dimethylformamide (DMF). […]

Springer – Spatial Engineering of Mammary Epithelial Cell Cultures with 3D Bioprinting Reveals Growth Control by Branch Point Proximity

Abstract https://link.springer.com/article/10.1007/s10911-024-09557-1 The three-dimensional (3D) structure of the ductal epithelium and the surrounding extracellular matrix (ECM) are integral aspects of the breast tissue, and they have important roles during mammary gland development, function and malignancy. However, the architecture of the branched mammary epithelial network is poorly recapitulated in the current in vitro models. 3D bioprinting […]

Royal Society of Chemistry / Green Chemistry – Employing photocurable biopolymers to engineer photosynthetic 3D-printed living materials for production of chemicals

https://pubs.rsc.org/en/content/articlehtml/2024/gc/d3gc04264b#fn1 Abstract Photosynthetic microorganisms, such as cyanobacteria and microalgae, have great potential as living cell factories for chemical and fuel production. Immobilisation of cells is an effective technique for enhancing productivity and longevity of the production system, as well as aiding in the separation of cells from the medium. Alginate crosslinked with divalent ions is […]

Advanced functional materials – Bioprinting Macroporous Hydrogel with Aqueous Two-Phase Emulsion-Based Bioink: In Vitro Mineralization and Differentiation Empowered by Phosphorylated Cellulose Nanofibrils

Abstract https://onlinelibrary.wiley.com/doi/full/10.1002/adfm.202400431 Aqueous two-phase emulsion (ATPE)-based bioinks, a creative innovation for bioprinting, enable the fabrication of complex 3D cell-laden hydrogels with macroporous structure, which promote cellular activities within the scaffold. However, these bioinks intrinsically lack stability and specific biofunctionality, potentially limiting their application for targeted tissue engineering. This study proposes a new perspective by introducing […]

Materials Advances – A comprehensive study on rheological properties of photocrosslinkable gallol-metal complexed hyaluronic acid-based biomaterial inks

Abstract https://pubs.rsc.org/en/Content/ArticleLanding/2024/MA/D4MA00273C This study describes the development of bioadhesive hydrogels as biomaterial inks, which combine catechol chemistry and metal coordination using gallic acid and hyaluronic acid. By controlling the phase of gelation, the properties of hydrogels can be modulated through pH and Fe3+ ion concentrations, thus allowing for diverse coordination states within the polymeric network. The […]

Lignin Esters and Their Composites with PLA

By Ellen SundströmMASTER’S THESISÅBO AKADEMI UNIVERSITYLaboratory of Molecular Science and Chemistry, Faculty of Science and Engineering2023 | 80 pages https://www.doria.fi/handle/10024/187902

SCIENCE SERIES PART II: 3D bioprinting for meniscus repair – Abstract

The menisci are important cartilage structures located on each side of the knee joint, as they provide the required cushion and shock absorbance, enhancing knee stability and distributing the weight of the body on the lower leg. They can bear up to five times the body weight during daily activities! Due to their poor blood […]

Taking A Closer Look Into Cartilage

Taking A Closer Look Into Cartilage The Brinter Team is excited to advance its 3D-bioprinted, cartilage bio-implants towards commercialization. In this informational series, we will delve into the various types of cartilage tissue and how bioprinting solutions are making a difference. Stay tuned for more informative content from our scientific team!

Published Book Chapter in Elsevier’s Handbook of Surgical Planning: A Collaborative Effort Towards Using 3D Bioprinting for Future Treatment of Osteoarthritis

Check out our newly published book chapter in Elsevier’s Handbook of Surgical Planning and 3D Printing discussing how 3D bioprinting can be used for future treatment of osteoarthritis! This chapter was written by an amazing team of scientists and engineers during the EU Horizon 2020 program funded RESTORE project, including Sanna Turunen, Tomi Kalpio, Carl Lindahl, Chirag […]

Brinter is challenging the status-quo for meniscus repair using 3D bioprinting.

Brinter is challenging the status-quo for meniscus repair using 3D bioprinting

Brinter is challenging the status-quo for meniscus repair using 3D bioprinting. For over 100 years, patients’ meniscus repairs have been done with non-biological materials, like metals, plastics, and polymers, that are rigid and limit patients’ flexibility and mobility. Brinter is changing this forever with 3D bioprinting durable and functional cartilaginous meniscus bio-implants. The meniscus acts […]

3D bioprinting of blood vessels. DI thesis

https://www.utupub.fi/handle/10024/174189 By Akseli Vainio & Brinter Ltd Publication Date: December 13, 2022 This thesis concentrates around 3D bioprinting of blood vessels using Brinter ONE platform and the triaxial toolhead. Samples were tested using UV curable silicone (for model testing) and telocollagen as a more physiological counterpart with cells. During this thesis also a guideline of […]